Dr. Martin J. McKeownBEng, MD, FRCP(C)

PPRI/UBC CHAIR in PARKINSON'S RESEARCH,

CLINICAL DIRECTOR, PACIFIC PARKINSON'S RESEARCH CENTER

 

Lab Members

 

Dr. Pratibha Surathi,  Clinical Neurology Fellow

 

 

Mahsa Shafiee, Post-Doctoral Researcher

 

 

 

 

Sue-Jin, PhD student, Neuroscience


 

About Sue-Jin:

 

I’ve been working in the lab as a PhD student in the Graduate Program in Neuroscience since 2012. I finished my masters training at the Institute of Brain Science, National Yang-Ming University, Taipei, Taiwan and then worked as a research assistant before I joined UBC. My research interest is using neuroimaging approach to investigate neuronal disorders with cognitive deficits. Especially apply novel techniques to analyze resting state fMRI data since I have been working on fMRI and resting state for 6 years before I entered PhD program. My current project focus on two populations: Parkinson’s disease and multiple sclerosis.

For Parkinson’s disease, we will be looking at non-motor aspects such as apathy, mood disorders, and executive functions. For multiple sclerosis, our primary goal is to look at the functional connectivity that is associated with cognitive dysfunction s. Meanwhile, we are going to apply the analysis approach that we are currently developing to study human brain connectivity. We believe that our research will benefit these two diseased populations and get more understanding of how the brain works and how the disease impacts the brain. As my future research interest, I would like to apply multimodal imaging approach to further study such as EEG/fMRI simultaneous recording and functional connectivity research.

Besides academia, I also participate several student associations. I’m VP Student Services in interdisciplinary graduate student network (iGSN) at UBC and Taiwanese graduate student association in Vancouver(TGSAvan). I like to help people and provide service to community. Through joining these associations, I’ve met a lot of different people and been able to gain extracurricular and cultural experience, which is one of the most valuable things while living in Canada. I have a very weird interest: cooking and taking photos of my food! After that, of course, I’ll upload the photos to facebook! Also, I am a mini expert of enriching recreational life. That’s also why I have a nick name from my friends: the little Wikipedia of eating, drinking, playing, and having fun!

Her accomplishments:

 

Awards received:

2007: Student Stipend Award, Annual Meeting of The International Society for Magnetic Resonance in Medicine

2007: Student Funding for International Conference, the National Science Council of Taiwan

2012: Scholarship for Studying Overseas, the Ministry of Education,Taiwan

2013: Second Prize of Neuroscience Extravaganza, UBC

Publications:

 Articles submitted to refereed journals

Sue‐Jin Lin, Tzu‐Chen Yeh, Chou‐Ming Cheng, Wen‐Jui Kuo, Jen‐Chuen Hsieh, Ton‐Ping Su, Low‐Tone Ho. Limited Default Network in Bipolar Disorder by BOLD‐based fMRI. Annual Meeting of the International Society for Magnetic Resonance in Medicine, Berlin, Germany, 2007.

Other refereed contributions

Sue‐Jin Lin. Constructing the Spatial Template of Default Network. Master Thesis, Taipei, Taiwan, 2008.

 Non-refereed contributions

Sue-Jin Lin, Aiping Liu, Sun Nee Tan, Jane Z Wang, Silke Appel-Cresswell, Martin J. McKeown. The Temporal Dynamics of Resting State Connectivity in Parkinson’s Disease. 18th International Congress of Parkinson's Disease and Movement Disorders, Stockholm, Sweden, 2014. (Guided Poster Tour Presentation)

Sue-Jin Lin, Aiping Liu, Jane Z Wang, David Leppert, Nicholas Seneca, Eduardo Vianna, Anna Dzyakanchuk, Shannon Kolind, Anthony Traboulsee, Martin J. McKeown. Compensatory remapping of fMRI functional connectivity during resting state in multiple sclerosis. Joint ACTRIMS-ECTRIMS Meeting, Boston, USA, 2014. 

Sue-Jin Lin, Jelmer Kok, Amanmeet Garg, Mirza Faisal Beg, Martin McKeown. Spatial Patterns of Diffusion Tensor Imaging in Parkinson’s Disease. Society for Neuroscience Annual meeting, San Diego, USA, 2013.

Tzu-ChenYeh, Sue-Jin Lin, Wen-Jui Kuo, Chou-Ming Cheng, Jen-ChuenHsieh, Low-Ton Ho.Gender Difference in Default Networks Detected by BOLD-based fMRI at 3T. Annual Meeting of the Organization for Human Brain Mapping, Melbourne, Australia, 2008.

Sue‐Jin Lin, Tzu‐Chen Yeh, Chou‐Ming Cheng, Jen‐Chuen Hsieh, Low‐Tone Ho. Searching the Reference Image for Selecting Default Network Components in fMRI. Annual Meeting of the Organization for Human Brain Mapping, Melbourne, Australia, 2008.

 

 

 Robert PhD student, Biomedical Engineering

 Presentations:

Microstructural White Matter Changes Predict Disease Progression in Parkinson’s DiseaseMicrostructural White Matter Changes Predict Disease Progression in Parkinson’s Disease, 23rd OHBM, 2017, Vancouver

Effects of Myelin Changes in Parkinson’s Disease on Motor Performance, 25th ISMRM, 2017, Honolulu

 

 

 

 

Soojin, PhD student, Biomedical Engineering

 

Soojin’s  work,  “Galvanic Vestibular Stimulation (GVS) Effects on Impaired Interhemispheric Connectivity in Parkinsons Disease”* has been selected as the top entry from North America. Next month, she will compete against the winners from Europe, Middle East/Africa and Asia to determine the worldwide top PhD paper at the annual IEEE Engineering in Medicine and Biology Society (EMBS) conference. The EMBS is the world’s largest international society of biomedical engineers with 11,000 members that reside in 97 countries around the world.

 

Publications:

Suhana Kamakari, Soojin Lee*, and Martin J. McKeown, Non-invasive Electrical Brain Modulation: A New Avenue for Treatment? University of Toronto Medical Journal, 93(2), 2016

Soojin Lee*, DianaJ.Kim, Daniel Svenkeson, Gabriel Parras, Meeko Mitsuko K. Oishi and Martin J. McKeown, Multifaceted effects of noisy galvanic vestibular stimulation on manual tracking behavior in Parkinson’s disease. Frontiers in systems neuroscience, 9(5), 2015.

Conference Presentations:

Soojin Lee*, Diana Kim, and Martin J. McKeown, Galvanic Vestibular Stimulation (GVS) effects on Impaired Interhemispheric Connectivity in Parkinson’s Disease. The 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, July 2017, Jeju, South Korea

Soojin Lee*, Z. Jane Wang and Martin J. McKeown, Removal of high voltage brain stimulation artifacts from simultaneous EEG recordings. 2nd International Brain Stimulation Conference, March 2017, Barcelona, Spain

Soojin Lee*, Jiayue Cai, DianaJ. Kim, Z. Jane Wang and Martin J. McKeown, Stimulation dependent, widespread cortical effects of galvanic vestibular stimulation in Parkinson’s disease. 4th World Parkinson Congress, Sept. 2016, Portland, USA

Soojin Lee*, Jiayue Cai, Diana J. Kim, Z. Jane Wang and Martin J. McKeown, Differential effects of noisy and sinusoidal Galvanic Vestibular Stimulation on resting state functional connectivity. 4th Annual Minnesota Neuromodulation Symposium, April 2016, Minneapolis, USA

 

 Stephanie, MSc Student, Neuroscience

 

 

Stephanie’s work, Galvanic Vestibular Stimulation: Effects On Postural Instability In Parkinson’s Disease” was selected as one of 6 (out of a field of >400) Best Abstract Awards presented at International Neuromodulation Society’s 13th World Congress held in Edinburgh, Scotland, May 27-June 1st.

 Conference presentations:

  • Tran, S., et al.. (2017). Galvanic Vestibular Stimulation: Effects on Postural Instability in Parkinson’s Disease. International Neuromodulation Society 13th World Congress, Edinburgh, Scotland

Oral presentations:

  • Tran, S., et al.. (2017). Effects of galvanic vestibular stimulation on postural instability in Parkinson’s disease. Faculty of Medicine Graduate Student Research Day. Vancouver, BC: Canada.
  • Tran, S.et al.. (2016). Galvanic vestibular stimulation as a potential treatment for Parkinson’s Disease postural instability and gait disorders. Innovation in Health Research and Technologies: Strategies for Successful Partnerships. Vancouver, BC: Canada.

 

Marcus Cheung, MSc student, Biomedical Engineering

Marcus

 

Oral presentations:

Marcus Cheung  and Martin J. McKeown. A Non-invasive and Non-Pharmacological Treatment for Parkinson’s Resting Tremor. 2017 Faculty of Medicine Graduate Student Research Day. May 26, 2017. Vancouver, BC: Canada.

 

MariaMSc Student, Neuroscience

 

Conference presentations:

Zhu, M., HajiHosseini, A., Schmok, J., Garg, S., Lee, S., and McKeown, M. Impaired frontal beta desynchronization during an incentive motivation task in apathetic patients with Parkinson's disease. J. 11th Annual CAN Meeting Canadian Association for Neuroscience. May 28-31, 2017. Montreal, QC: Canada.

Oral presentations:

Zhu, M., HajiHosseini, A., Garg, S., and McKeown, M. J. Altered beta desynchronization during an incentive motivation task in apathetic patients with Parkinson's disease. 2017 Faculty of Medicine Graduate Student Research Day. May 26, 2017. Vancouver, BC: Canada.

Zhu, M., HajiHosseini, A., Garg, S., and McKeown, M. Impaired frontal beta desynchronization during an incentive motivation task in apathetic patients with Parkinson's disease. Neurology Resident Research Day. May 10, 2017. Vancouver, BC: Canada.

Zhu, M. and McKeown, M. J. GVS: A prospective treatment for apathy in Parkinson's disease. Innovation in Health Research and Technologies: Strategies for Successful Partnerships. May 27, 2016. Vancouver, BC: Canada.

 

Emma Kiss, BSc- Research Assistant

 

Conference presentations:

Emma M. Kiss, Christina B. Jones, Soojin Lee and Martin J. McKeown. Interhemispheric connectivity (IHC) derived from portable EEG as a potential neurofeedback tool for Parkinson’s disease. International Neuromodulation Society 13th World Congress, May 29-Jun 1, 2017. Edinburgh, Scotland.

 

 

 

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